CATEGORY

Cell lines

MOST COMMON MOUSE MODEL

Animal Tumor Cell Lines

General Info

Animal Tumor Cell Lines provide reliable oncology models to study cancer metabolism, proliferation, and therapeutic responses. With 445+ available lines spanning multiple animal species such as mouse, rat, bovine, and canine, these models offer a broad and versatile platform for cancer research. Compared with normal cells, tumor cells exhibit abnormal growth and signaling, making them valuable in translational research and drug discovery. AcceGen’s extensive catalog ensures researchers can access high-quality cell lines to support preclinical studies with greater accuracy and reproducibility.

Benefits:
– Over 445 established animal tumor cell lines across diverse species
– Includes carcinoma and normal tissue cell lines for comparative research
– Reliable cancer models for metabolism, signaling, and therapeutic testing
– Comprehensive options supporting translational oncology research

📩 Please contact i-DNA – the official distributor of AcceGen – for further information or quotation.

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MOST COMMON MOUSE MODEL

CAR-T Cell Therapy

General Info

CAR-T cell therapy is revolutionizing cancer treatment by engineering T cells with chimeric antigen receptors (CARs) that target tumor-associated antigens with specificity. Our end-to-end oncology CAR-T research solutions — from vector construction, virus production, reporter assays, functional bioassays, cell lines, antibodies, and cytokines to workflow-optimized kits — help accomplish supported, reproducible results in your CAR-T projects.
Our assay kits, reagents, and antibodies provide increased sensitivity and efficiency, offering unmatched reliability compared to conventional market solutions.

Benefits:

Complete workflow support: CAR design, transduction, expansion, and functional validation.

High-quality, highly characterized reagents optimized for stability, sterility, and lot-to-lot consistency.

Fit-for-purpose validated assays across multiple applications: finding T-cell potency, screening for cytokine release, and more.

Pre-made stable cell lines, including knockout and reporter models; assay-ready solutions and ready-to-use ELISA kits for detection and quantification.

📩 Please contact i-DNA – the official distributor of Innovative Research – for further information or quotation.

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MOST COMMON MOUSE MODEL

CDX Models

General Info

Bioluminescent cell lines for CDX models are essential tools for in vivo studies aimed at evaluating anti-tumor efficacy, pharmacokinetics/pharmacodynamics, toxicity, and other characteristics of therapeutic candidates. These engineered human-derived cell lines constitutively express firefly luciferase or eGFP, enabling convenient bioluminescence or fluorescence imaging of tumor progression in CDX mouse models. Applicable across a wide range of therapeutic modalities—including small molecules, antibodies, and CAR-T therapies—these cell lines support rapid, sensitive, and quantitative readouts. CDX workflows can be performed using mouse or rat systems under subcutaneous, disseminated, or orthotopic conditions, providing flexible modeling options.

✅ Benefits:

– Engineered luciferase-expressing cell lines optimized for bioluminescent tumor imaging
– Derived from single-clone origins to ensure uniform luciferase expression and consistent readouts
– Includes validated human cell lines with optimized thaw/growth recommendations and low endotoxin
– Supports well-established CDX models using lines such as Raji, MM.1S, MC38, K562, Jurkat, SKOV-3, and more

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.

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MOST COMMON MOUSE MODEL

Cell Lysate

General Info

Creative Biogene offers a comprehensive range of cell lysates, designed to support diverse research applications in protein analysis and functional studies. The collection includes both overexpression cell lysates containing recombinant proteins and knockout cell lysates generated using CRISPR/Cas9 technology. These lysates are produced through precise gene delivery and homogenization processes, ensuring high-quality and consistent products ideal for western blotting, assay development, and control experiments. Compared to conventional methods, these ready-to-use lysates provide researchers with reliable, reproducible, and time-saving solutions.

Benefits:
– Wide selection of overexpression and knockout cell lysates for various targets
– Produced with advanced CRISPR/Cas9 technology for accuracy and stability
– High-quality homogenization in RIPA buffer, ensuring consistency
– Ideal for western blot positive/negative controls and additional research applications

📩 Please contact i-DNA – the official distributor of Creative Biogene – for further information or quotation.

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MOST COMMON MOUSE MODEL

Cell Signaling Pathway

General Info

Cell signaling pathway cell lines from BPS Bioscience are powerful tools for studying protein interactions, gene activation, viral infection, and cellular communication. With over 250 validated stable cell lines, they provide researchers with highly reproducible and biologically relevant data. Compared to conventional assays, these cell lines offer superior precision, consistency, and adaptability for applications in immunotherapy, CAR-T research, metabolism, neuroscience, and beyond.

Benefits:
– Extensive portfolio of over 250 stable and validated cell lines
– High reproducibility and minimized end-user troubleshooting
– Ideal for studying immune response, viral infection, and signal transduction
– Compatible with multiple research areas including CAR-T and iPSC-derived models

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.

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MOST COMMON MOUSE MODEL

Coronavirus

General Info

Understanding the interactions between viral pathogens and host cells is critical for advancing antiviral drug and vaccine development. BPS Bioscience provides Human ACE2 stable cell lines that enable precise studies of SARS-CoV-1, SARS-CoV-2, and HCoV-NL63 mechanisms in cellular models. These cell lines offer consistent, reproducible expression and can be combined with Spike pseudotyped luciferase reporter lentivirus for detailed investigation of viral entry and infection pathways. Compared to conventional models, these stable lines deliver higher reliability and flexibility for drug screening, antibody testing, and mechanistic studies.

Benefits:
– Stable ACE2-expressing cell lines for coronavirus research
– Compatible with Spike pseudotyped reporter systems for viral entry assays
– Ideal for drug screening, antibody validation, and neutralization studies
– Consistent, reproducible expression ensuring reliable results

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.

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MOST COMMON MOUSE MODEL

CRISPR

General Info

CRISPR-Cas9 is a groundbreaking gene-editing technology that enables precise and efficient modifications of cellular DNA. Leveraging natural bacterial defense mechanisms, this system allows researchers to specifically target and edit genes with unprecedented accuracy. BPS Bioscience provides a comprehensive CRISPR-Cas9 platform including Cas9-expressing cell lines, SAM-ready lines, and knockout cell lines, alongside recombinant proteins and custom services. Compared to conventional genetic tools, CRISPR-Cas9 offers higher precision, versatility, and scalability, making it a key driver in modern biomedical research and biotechnology.

Benefits:
– Highly precise gene editing with targeted DNA modifications
– Wide applications in research, medicine, and biotechnology
– Ready-to-use Cas9 cell lines, SAM-ready lines, and knockout libraries
– Recombinant Cas proteins (Cas9, Cas12, Cas13) and customizable solutions

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.

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MOST COMMON MOUSE MODEL

Gene Knockdown Stable Cell Lines

General Info

Gene knockdown stable cell lines are essential tools for studying gene function, building disease models, biopharmaceutical research, and drug discovery. By using shRNA technology with low degradation and turnover rates, these cell lines ensure reliable and reproducible gene silencing. Developed and validated by Creative Biogene’s experienced scientific team, these stable cell lines provide genetic consistency and high quality, minimizing variability across experiments. Compared with conventional knockdown systems, they offer long-term stability and contamination-free cultures, making them highly trusted in global research.

Benefits:
– One-stop service with expert support from design to final stable cell line generation.
– Professional research team with extensive experience in molecular and cell biology.
– Verified genetic stability across more than 25 genes.
– High-quality, mycoplasma-free stable cell lines for reliable results.

📩 Please contact i-DNA – the official distributor of Creative Biogene – for further information or quotation.

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MOST COMMON MOUSE MODEL

Gene Knockout Stable Cell Lines

General Info

Gene knockout stable cell lines are advanced tools designed using the CRISPR/Cas9 system, the most widely adopted method for precise genome editing. These cell lines allow researchers to disrupt specific genes, enabling functional studies, drug screening, and disease model development. Creative Biogene provides rigorously validated knockout stable cell lines that ensure genetic stability, high reproducibility, and no mycoplasma contamination. With extensive expertise, our team delivers reliable solutions that accelerate research outcomes compared to conventional approaches.

Advantages:
– One-stop customized service from gRNA design to stable clone generation
– Backed by experienced molecular and cell biology research team
– Rigorously tested and validated for genetic stability
– High-quality cell lines with no mycoplasma contamination

📩 Please contact i-DNA – the official distributor of Creative Biogene – for further information or quotation.

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MOST COMMON MOUSE MODEL

Gene Overexpression Stable Cell Lines

General Info

Gene overexpression stable cell lines are essential tools for biology research, enabling protein engineering, recombinant antibody development, drug discovery, and various functional studies. Creative Biogene provides reliable and efficient stable expression of genes of interest (GOI) through plasmid transfection or lentivirus transduction. With extensive experience, our scientists deliver high-quality GPCR, reporter, and ion channel stable cell lines at competitive pricing and with rapid turnaround, outperforming many alternatives in the market. These stable systems ensure consistent gene expression, saving valuable time and resources for researchers worldwide.

Benefits:
– Stable expression of target genes for long-term research applications
– Wide coverage of GPCR, reporter, and ion channel stable cell lines
– Cost-effective solution with competitive turnaround times
– Backed by experienced scientists and advanced laboratory infrastructure

📩 Please contact i-DNA – the official distributor of Creative Biogene – for further information or quotation.

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MOST COMMON MOUSE MODEL

Human Tumor Cell Lines

General Info

Animal Tumor Cell Lines provide reliable oncology models to study cancer metabolism, proliferation, and therapeutic responses. With 445+ available lines spanning multiple animal species such as mouse, rat, bovine, and canine, these models offer a broad and versatile platform for cancer research. Compared with normal cells, tumor cells exhibit abnormal growth and signaling, making them valuable in translational research and drug discovery. AcceGen’s extensive catalog ensures researchers can access high-quality cell lines to support preclinical studies with greater accuracy and reproducibility.

Benefits:
– Over 445 established animal tumor cell lines across diverse species
– Includes carcinoma and normal tissue cell lines for comparative research
– Reliable cancer models for metabolism, signaling, and therapeutic testing
– Comprehensive options supporting translational oncology research

📩 Please contact i-DNA – the official distributor of AcceGen – for further information or quotation.

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MOST COMMON MOUSE MODEL

Immunotherapy

General Info

Immunotherapy is transforming cancer treatment by harnessing the power of the body’s immune system to fight tumors. Unlike traditional therapies such as surgery, chemotherapy, or radiation, immunotherapy targets abnormal cells with greater precision, often resulting in fewer side effects and improved long-term outcomes. BPS Bioscience offers a comprehensive portfolio of solutions supporting checkpoint inhibitors, CAR-T, TCR-T therapies, and antibody-based approaches, empowering researchers to advance immuno-oncology with cutting-edge tools. Compared to conventional methods, immunotherapy solutions deliver higher specificity and stronger therapeutic potential.

Benefits:
– Harnesses the body’s immune system for targeted cancer therapy
– Reduces side effects compared to traditional treatments
– Comprehensive product portfolio: checkpoint molecules, CAR-T, TCR-T, ADC approaches
– Enables novel therapeutic discoveries and better patient outcomes

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.

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MOST COMMON MOUSE MODEL

ion-channel

General Info

Ion channel and membrane transport cell lines from BPS Bioscience provide robust and reliable tools for studying ion flux, signal transduction, and membrane dynamics. These validated recombinant cell lines cover a broad range of ion channels, including sodium, potassium, calcium, and chloride channels, enabling precise functional assays for both basic research and drug discovery. Compared to conventional models, BPS ion channel cell lines deliver reproducibility, high expression levels, and tailored options to support advanced pharmacological profiling. They are ideal for investigating mechanisms of channelopathies and screening novel therapeutics targeting ion channel dysfunctions.

Benefits:
– Wide range of recombinant ion channel cell lines (sodium, potassium, calcium, chloride, etc.)
– High reproducibility and validated performance for research and drug screening
– Reliable tools for studying ion flux, signaling, and transport mechanisms
– Supports discovery of new therapeutics for channelopathies and membrane-related disorders

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.

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MOST COMMON MOUSE MODEL

iPSC-Derived Cells

General Info

Induced pluripotent stem cells (iPSCs), pioneered by Nobel Prize winner Shinya Yamanaka, represent a groundbreaking technology for drug discovery and regenerative medicine. Unlike conventional models, iPSCs can differentiate into various cell types, enabling researchers to study disease mechanisms, toxicity, and therapeutic strategies in a more physiologically relevant system. BPS Bioscience provides iPSC-derived cells that improve experimental fidelity, reduce reliance on animal models, and accelerate the development of targeted therapies. These cells offer unparalleled flexibility and reproducibility for advanced biomedical research.

Benefits:
– Improved model fidelity over traditional cell lines and assays
– Higher throughput and reduced costs compared to animal models
– Applicable to toxicity screening, disease modeling, and cell therapy development
– Reliable tools for advancing drug discovery and regenerative medicine research

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.

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MOST COMMON MOUSE MODEL

Kinases

General Info

Kinases play a crucial role in regulating nearly all aspects of cell biology, including division, metabolism, signaling, and communication. BPS Bioscience offers one of the most comprehensive kinase product portfolios, spanning lipid kinases, nucleotide kinases, carbohydrate kinases, and protein kinases such as tyrosine and serine/threonine kinases. Each product undergoes rigorous validation and quality control to ensure reliable results, optimized for both basic research and drug discovery applications. Compared to traditional assay providers, BPS delivers highly specific, reproducible, and ready-to-use kinase solutions that accelerate biomedical breakthroughs.

Benefits:
– Extensive kinase portfolio covering over 500 unique enzymes
– Validated through strict QC for reproducibility and accuracy
– High-throughput optimized assay kits with homogeneous no-wash formats
– Flexible tools for drug discovery, target screening, and functional studies

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.

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MOST COMMON MOUSE MODEL

Metabolic Enzymes

General Info

Metabolic enzymes are essential biological catalysts that regulate critical processes such as energy production, biosynthesis, detoxification, and overall cellular homeostasis. BPS Bioscience provides a comprehensive portfolio of metabolic enzymes, assay kits, recombinant proteins, and inhibitors to accelerate drug discovery and therapeutic research. Compared to the current market, these products stand out for their extensive validation, optimized performance, and broad applicability in studying metabolic disorders, cancer, and chronic diseases.

Benefits:
– Wide selection of high-purity recombinant metabolic enzymes.
– Ready-to-use inhibitor screening and complete assay kits for efficient discovery.
– Optimized cell lines for studying metabolic signaling pathways.
– Validated inhibitors for precise evaluation of metabolic enzyme activity.

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.

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MOST COMMON MOUSE MODEL

miRNA Overexpression Stable Cell Lines

General Info

miRNA Overexpression Stable Cell Lines are advanced tools for studying gene regulation, cellular processes, and disease mechanisms by enabling consistent overexpression of specific microRNAs (miRNAs). These stable cell lines mimic natural miRNA pathways and provide reliable models for applications in cancer biology, apoptosis, stress response, and cell differentiation research. Developed with rigorous validation, they ensure reproducibility and stability, offering superior advantages compared to transient transfection methods.

Benefits:
– Stable and long-term expression of target miRNAs
– Reliable models for studying proliferation, differentiation, apoptosis, and stress pathways
– Reduced variability compared to transient transfection approaches
– Available for human, mouse, and rat models to support diverse research needs

📩 Please contact i-DNA – the official distributor of Creative Biogene – for further information or quotation.

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MOST COMMON MOUSE MODEL

Neuroscience

General Info

Neuroscience research is advancing the understanding of CNS-related disorders by exploring the structure, function, and development of the central nervous system. BPS Bioscience offers a wide portfolio of innovative products including specialized cell lines, high-titer AAVs, assay kits, and recombinant proteins. These solutions empower scientists to uncover disease mechanisms, identify novel therapeutic targets, and accelerate the discovery of treatments for neurological and psychiatric conditions. Compared to existing market solutions, BPS products stand out for their diversity, validation, and high compatibility with CRISPR and screening platforms.

Benefits:
– High-throughput screening cell lines for receptor/pathway inhibitor studies.
– CRISPR/CRE luciferase reporter HEK293 cell lines and Cas9-expressing Neuro2A cell lines.
– CNS-targeting AAV vectors and fluorescent reporter AAVs for visualization and quantification.
– Comprehensive biochemical assay kits and recombinant proteins for neuroscience research.

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.

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MOST COMMON MOUSE MODEL

Primary Cells

General Info

BPS Bioscience provides highly characterized primary cells, including enriched CD4+ and CD8+ T cells, PBMCs, and ready-to-use CAR-T cells for advanced immunology and cell therapy research. These primary cells are derived from healthy donors, tested negative for major pathogens, and manufactured under stringent quality control to ensure consistency and reproducibility. With high-titer lentiviral transduction, CAR-T cells from BPS offer superior performance in cytotoxicity assays and co-culture experiments. Compared to market alternatives, BPS primary cells stand out with validated purity, scalability, and application in cutting-edge therapeutic research.

Benefits:
– Enriched CD4+ and CD8+ T cells, PBMCs, and functional CAR-T cells.
– Negative screening for major human pathogens ensures reliability.
– Optimized for cytotoxicity assays, drug testing, and co-culture models.
– High consistency and reproducibility across batches for robust research outcomes.

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.

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MOST COMMON MOUSE MODEL

Proteases

General Info

Proteases, also known as peptidases or proteinases, are essential enzymes that catalyze protein breakdown into peptides and amino acids, playing a vital role in diverse biological pathways. From cell signaling to extracellular matrix remodeling and viral protein degradation, proteases are indispensable in both basic research and therapeutic applications. BPS Bioscience offers a comprehensive portfolio of protease families, including assay kits, recombinant proteins, and inhibitors, optimized for high-throughput screening and reliable results. Compared to conventional assays, BPS solutions provide enhanced sensitivity, reproducibility, and detailed protocols, accelerating drug discovery and development.

Benefits:
– Broad portfolio covering key protease families with validated assays.
– High-sensitivity fluorogenic assays optimized for screening applications.
– Support for research in viral control, neurodegenerative diseases, and cancer.
– Detailed protocols and simplified workflows for reliable, reproducible results.

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.

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