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The Future of 3Rs: Integrated Biology Systems
Engineering the 3Rs through System Design — Not Just Compliance
At the SALAS Scientific Conference 2026, Thuan D. Bui, PhD, MBA shared one key idea:
👉 3Rs are not guidelines — they are system outputs.
They don’t fail because of lack of awareness,
but because of fragmented systems.
• Reduce → better design
• Replace → validated alternatives (AI, organoids)
• Reuse → integrated data
👉 Weak interfaces = failed 3Rs
⸻
The future is Integrated Biology:
AI + Animal + Organoid + Data
At i-DN...
