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CDX Models

Bioluminescent cell lines for CDX models are essential tools for in vivo studies aimed at evaluating anti-tumor efficacy, pharmacokinetics/pharmacodynamics, toxicity, and other characteristics of therapeutic candidates. These engineered human-derived cell lines constitutively express firefly luciferase or eGFP, enabling convenient bioluminescence or fluorescence imaging of tumor progression in CDX mouse models. Applicable across a wide range of therapeutic modalities—including small molecules, antibodies, and CAR-T therapies—these cell lines support rapid, sensitive, and quantitative readouts. CDX workflows can be performed using mouse or rat systems under subcutaneous, disseminated, or orthotopic conditions, providing flexible modeling options.

✅ Benefits:

– Engineered luciferase-expressing cell lines optimized for bioluminescent tumor imaging
– Derived from single-clone origins to ensure uniform luciferase expression and consistent readouts
– Includes validated human cell lines with optimized thaw/growth recommendations and low endotoxin
– Supports well-established CDX models using lines such as Raji, MM.1S, MC38, K562, Jurkat, SKOV-3, and more

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.

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CDX Models

Bioluminescent cell lines for CDX models are essential tools for in vivo studies aimed at evaluating anti-tumor efficacy, pharmacokinetics/pharmacodynamics, toxicity, and other characteristics of therapeutic candidates. These engineered human-derived cell lines constitutively express firefly luciferase or eGFP, enabling convenient bioluminescence or fluorescence imaging of tumor progression in CDX mouse models. Applicable across a wide range of therapeutic modalities—including small molecules, antibodies, and CAR-T therapies—these cell lines support rapid, sensitive, and quantitative readouts. CDX workflows can be performed using mouse or rat systems under subcutaneous, disseminated, or orthotopic conditions, providing flexible modeling options.

✅ Benefits:

– Engineered luciferase-expressing cell lines optimized for bioluminescent tumor imaging
– Derived from single-clone origins to ensure uniform luciferase expression and consistent readouts
– Includes validated human cell lines with optimized thaw/growth recommendations and low endotoxin
– Supports well-established CDX models using lines such as Raji, MM.1S, MC38, K562, Jurkat, SKOV-3, and more

📩 Please contact i-DNA – the official distributor of BPS Bioscience – for further information or quotation.